Today’s case is a 4-year-old female neutered Lhasa Apso with two-week history of cough. What’s your diagnosis?
There is a marked bronchointerstitial pattern throughout the lungs. The bronchial walls appear thickened with examples of tram tracks and donuts. There is also a patchy interstitial pattern present.
- infectious or non-infectious airway-associated disease (allergic bronchitis, eosinophilic bronchopneumopathy)
Bronchial lavage: Marked eosinophilic inflammation with increased mucus
Pathology Comments:Differentials include hypersensitivity/allergic response, primary eosinophilic pulmonary granulomatosis or inflammation secondary to underlying infectious disease including fungal, atypical bacterial or parasitic causes. Paraneoplastic responses can also lead to eosinophilic inflammation although this is thought to be less likely in this case. No infectious agents or overtly neoplastic cells are observed.