Today’s case is a 10-year-old female neutered Husky. The patient has a prolapsed 3rd eyelid on the left and suspected trigeminal neuropathy. CBC shows a 60,000 lymphocyte count. What are your findings?
There is a diffuse interstitial pattern throughout the lungs. The cardiovascular structures appear normal. No other abnormalities are noted in the musculoskeletal structures, mediastinum, or pleural space.
The high lymphocyte count is consistent with round cell neoplasia, making lymphoma the most likely cause of the interstitial pattern. Inflammatory or degenerative disease could also be considered.
- Large cell B-cell lymphoma (from mandibular lymph node aspirate)
- Differentials include leukemia (small lymphocytes in peripheral blood) with transformation to lymphoma, or concurrent leukemia and lymphoma.