This week’s case is a 13-year-old female neutered Siamese cat with weight loss and tachypnea. Try to characterize the pulmonary pattern in this case. It’s quite challenging, but it gives you some clue to the disease processes.
On radigoraphs of the thorax, there is dilation of the trachea with undulation in the thorax on the right lateral projection. There is a diffuse bronchial pattern with multiple regions of rounded radiolucency, especially in the cranioventral thorax. The lungs appear hyperinflated. The cardiovascular structures appear normal. There is poor detail in the peritoneal space and the animal is in thin body condition.
Hyperinflation and bronchointerstitial pattern with pulmonary emphysema may be secondary to chronic lower airway disease with inflammation. The tracheal dilation is likely secondary to the increased respiratory effort and/or tracheomalacial.
- Severe extensive fibrosis with bulla formation
- Infiltration with Langerhans cell histiocytes causing pulmonary disease
Feline Pulmonary Langerhans Cell Histiocytosis with Multiorgan Involvement. Busch MDM, Reilly CM, Luff JA, Moore PF. Vet Pathol (2008) 45: 816.